During conventional pharmacologic dose corticosteroid therapy, ACTH production is inhibited with subsequent suppression of cortisol production by the adrenal cortex. Recovery time for normal HPA activity is variable depending upon the dose and duration of treatment. During this time the patient is vulnerable to any stressful situation. Although it has been shown that there is considerably less adrenal suppression following a single morning dose of prednisolone (10 mg) as opposed to a quarter of that dose administered every six hours, there is evidence that some suppressive effect on adrenal activity may be carried over into the following day when pharmacologic doses are used. Further, it has been shown that a single dose of certain corticosteroids will produce adrenal cortical suppression for two or more days. Other corticoids, including methylprednisolone, hydrocortisone, prednisone, and prednisolone, are considered to be short acting (producing adrenal cortical suppression for 1¼ to 1½ days following a single dose) and thus are recommended for alternate day therapy.
Thank you for bringing this up, I am about to write a detailed review about the brand “Crazy Mass” and Yes i have used crazy mass products, a while ago i wanted to mix crazy mass’s D-Anaoxn Elite Series in my bulking cycle which usually has d-bal from crazy bulk. TBH D-anaoxn gave me this full feeling, I mean i couldn’t eat more then 2 meals and i was burping all the time like i had a something rotten made me feel a little sick, although despite of less eating i was able to increase my bench significantly put up some quick muscle too. But do i recommend it over crazy bulk d-bal? May be Naah,
In the 1970s, bodybuilding had major publicity thanks to the appearance of Arnold Schwarzenegger , Franco Columbu , Lou Ferrigno , and others in the 1977 docudrama Pumping Iron . By this time, the IFBB dominated the competitive bodybuilding landscape and the Amateur Athletic Union (AAU) took a back seat. The National Physique Committee (NPC) was formed in 1981 by Jim Manion ,  who had just stepped down as chairman of the AAU Physique Committee. The NPC has gone on to become the most successful bodybuilding organization in America, and is the amateur division of the IFBB. The late 1980s and early 1990s saw the decline of AAU-sponsored bodybuilding contests. In 1999, the AAU voted to discontinue its bodybuilding events.