One study has been conducted in athletes given D-aspartic acid supplementation at a dose of 3g daily for 28 days, and there was a failure to increase testosterone concentrations when measured at 28 days.  This study noted a statistically significant induction of serum D-aspartate oxidase (DAO) which degrades D-aspartate  to a near doubling;  this suggests a possible form of negative feedback, and aromatase (may also be induced by D-aspartic acid  ) was not thought to contribute due to estrogen being unchanged.
The Department of Molecular Medicine, University of Malaya in Malaysia conducted a study on the protective action of Saluyot against thioacetamide-induced hepatotoxicity in rats to determine if Saluyot can indeed help treat jaundice. An ethanol extract of Saluyot has been administered to rats subjected to liver damage by thioacetamide. Results had shown that the rats when compared to a control group showed resistance against liver lesions, cell necrosis and inflammation. The study further suggests that the protective effect of Saluyot extract in chemical-induced liver damage might be contributed to its modulation on detoxification enzymes and its antioxidant and free radical scavenger effects. Moreover, it confirms a scientific basis for the traditional use of Saluyot for the treatment of liver disorders. (Molecules. 2012: Ipomoea aquatica extract shows protective action against thioacetamide-induced hepatotoxicity)