Another non-food protein reaction, urushiol-induced contact dermatitis , originates after contact with poison ivy , eastern poison oak , western poison oak , or poison sumac . Urushiol , which is not itself a protein, acts as a hapten and chemically reacts with, binds to, and changes the shape of integral membrane proteins on exposed skin cells. The immune system does not recognize the affected cells as normal parts of the body, causing a T-cell -mediated immune response .  Of these poisonous plants, sumac is the most virulent.  The resulting dermatological response to the reaction between urushiol and membrane proteins includes redness, swelling, papules , vesicles , blisters , and streaking. 
We don’t endorse being like Rich Piana, and frankly neither does he, but this one of a kind monster of a man is becoming harder and harder to hate. In a world filled with charlatans, guys who pretend they’re all natural to sell you supplements, Photoshoppers , and the list goes on – Rich Piana is a breath of fresh air. He tells it like it is and he’s not afraid to be himself, even when he takes massive amounts of heat for it. He was recently featured in a paper that said he weighted 310 pounds, so we’re making the safe assumption that he’s put on at least 5 more since then, since this guy never stops growing.
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