Idiopathic Guttate Hypomelanosis (IGH) is a benign and asymptomatic skin manifestation characterized as diffuse hypopigmented macules, or white spots. The size of the lesions varies from 1-10mm, but are most commonly 1-3 mm in diameter. It is most commonly seen in fair-skinned individuals and appears to be related to cumulative sun exposure rather than just age. Interestingly, this condition manifests in women earlier than men, probably because their legs are more exposed. However, as age increases the incidence of IGH in women and in men is the same. IGH can also be seen in older dark-skinned individuals, but usually at more advanced age. The distribution of IGH can be seen along most exposed areas of the body. These include areas of the arms, legs, upper back, and face. Lesions are usually seen first along the anterior portion of the legs and then seen on the arms, back and face.
Prednisone is a drug that belongs to the corticosteroid drug class, and is an
anti-inflammatory and immune system suppressant. It's used to treat a variety of diseases and conditions, for example: inflammatory bowel disease (Crohn's
disease and ulcerative colitis), lupus, asthma, cancers, and several types of
Common side effects are weight gain, headache, fluid retention, and muscle weakness. Other effects and adverse events include glaucoma, cataracts, obesity, facial hair growth, moon face, and growth retardation in children. This medicine also causes psychiatric problems, for example: depression, insomnia, mood swings, personality changes, and psychotic behavior. Serious side effects include reactions to diabetes drugs, infections, and necrosis of the hips and joints.
Corticosteroids like prednisone, have many drug interactions; examples include: estrogens, phenytoin (Dilantin), diuretics, warfarin (Coumadin, Jantoven), and diabetes drugs. Prednisone is available as tablets of 1, , 10, 20, and 50 mg; extended release tablets of 1, 2, and 5mg; and oral solution of 5mg/5ml. It's use during the first trimester of pregnancy may cause cleft palate. This medicine is secreted in breast milk and can cause side effects in infants who are nursing. You should not stop taking prednisone abruptly because it can cause withdrawal symptoms and adrenal failure. Talk with your doctor, pharmacist, or other medical professional if you have questions about beta-blockers. Talk with your doctor, pharmacist, or other medical professional if you have questions about prednisone.
If you notice other effects not listed above, contact your doctor or pharmacist. In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.