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it is important to know the degree of increases in WBC counts, it is just as
important to be able to appropriately assess the WBC differential, so as to
avoid missing a treatable condition. The above increases in neutrophils
are made up by a small portion of immature (bands) WBC that predominately came
from the bone marrow. However, this contribution of bands does not
usually cause the same degree of a "left shift" that is normally
associated with presence of a bacterial In addition,
glucocorticoid induced leukocytosis is generally not associated with increases
in temperature or worsening in the condition that is being appropriately treated.
Therefore, it is important for the clinician to put all of these factors in
context when assessing, monitoring and treating the patient's medical
Total Bilirubin () is the sum of conjugated and unconjugated serum bilirubin. One of the byproducts of red blood cell breakdown is bilirubin. Bilirubin is made in the bone marrow, liver, or spleen and is transported by albumin to the liver in the form of unconjugated bilirubin. Once in the liver, sugars bind to the unconjugated bilirubin, turning it to conjugated bilirubin. It is then excreted from the gall bladder into the small intestine. Eventually, it is excreted in the feces or urine. Excess bilirubin causes a yellowing of the skin and the whites of the eyes called jaundice.