Clinical endocrinology is the study of the endocrine system, its function, and its diseases or abnormalities as related to patient care. In other words, a clinical endocrinologist would spend most of his/her time seeing patients who have one or more disorders of the endocrine system. The endocrine system can be defined as those organs in the body which release hormones that regulate many of the body’s functions, like the testes and ovaries, the pancreas, the pituitary gland , and the thyroid gland. Those who specialize in clinical endocrinology are highly trained physicians. Additional conditions, on which clinical endocrinology concentrates, include thyroid disorders , which may have significant effect on all body functions when ignored. Hormone disorders of other types can be treated by endocrinologists. Problems with estrogen of progesterone production in the female body could cause many symptoms like reduced fertility .
Salicylates can cause various metabolic changes such as changes in acid-base balance and electrolyte balance, which can, in turn, alter blood pressure and heart rate. However, mechanism of action seems to be as follows in respect of the thyroid hormones.
Thyroxine hormone binds to certain hormones in the blood called TBG Proteins. However, thyroxine can be displaced from TBG Proteins by certain substances such as drugs. In addition, if the amount of TBG Protein changes, this will alter the amount of thyroxine in the blood.
Some products used to treat acne and skin disorders contain Salicylates, but since these are used topically as are Oil of Wintergreen (typically found in Relax, Deep Heat etc.) we do not know what effects these have on the thyroid.
The maximum recommended frequency of using Duromine capsules is once daily. The use of Duromine more than twice a day can cause side effects.