Anabolic steroid induced pancreatitis

k) Impotence
When first administering steroids, a man will have an increase in sexual function. This unfortunately is only temporary as your body becomes used to the steroid in its system. With prolonged use of a steroid, eventually, the man will feel less sexual desire, and will be less capable of maintaining an erection. Luckily, this is only temporary as well and can even be totally prevented with the use of substance such as Gonakor and HCG. Also when the steroid use is discontinued, the body’s natural level of testosterone (like the immune system) will certainly be suppressed.

The use of Anabolic Androgenic Steroids (AAS) has been linked to causing myocardial infarction, sudden cardiac death, ventricular fibrillation with exercise, atrial fibrillation, cardiac tamponade, and development of dilated cardiomyopathy [5]. AAS like other endogenous steroids influence left ventricular hypertrophic response through the androgen receptor. Androgen receptors are found on skeletal muscle and also on cardiac myocytes. They cause alterations in heart structure, including left ventricular hypertrophy, dilation which can cause impaired contraction and relaxation [6]. Anabolic steroids can induce an unfavorable enlargement and thickening of the left ventricle, which loses its diastolic properties with the mass increase [7]. AAS can also cause hypertension, dyslipidemia, and impaired fasting glucose [8]. The effect of anabolic androgenic steroids on the cardiovascular system has been well described in the literature; however, the knowledge of these effects amongst amateur sports participants is poor [9].  A qualitative, cross-sectional, observational study using an anonymous online questionnaire completed by amateur sports participants enrolled in competitive sports teams at an Irish university demonstrated that one-third of respondents personally knew someone that uses anabolic steroids, however 59% of participants were never advised about their health effects [9]. The majority (59%) of respondents obtained their nutritional advice from Internet sites or friends and only 26% of respondents knew about the blood pressure and cholesterol effects of anabolic steroid use [9].

Clomid is a SERM and works well for men with hypogonadism/testosterone replacement therapy (TRT)- both for men who wish to maintain fertility and for standard TRT. This medication is a classic part of Post Cycle Therapy (PCT). It has been shown more recently in the literature to be a useful agent to wean men off AAS World J Nephrol. 2015 May 6; 4(2): 245–253. Today, we are seeing many general physicians in America using Clomid and other ancillary agents like HCG to help reduce suffering and recover men diagnosed with anabolic steroid induced hypogonadism (ASIH). In addition to this, there is a place for AIs in the management of men on TRT. Some men who are on appropriate-dose physiologic testosterone replacement can manifest superphysiologic levels of estrogen, despite normal testosterone levels. Remember as discussed above, testosterone/estrogen balance is a multifactorial issue and some men simply have genes for becoming “out of balance” on TRT. When used in a very cautious and limited fashion, in men who have low heart disease risks- specifically normal HDL levels, the addition of a low dose AI to TRT can lead to improvements in quality of life via balancing androgen/estrogen levels. When this is done by an expert physician and the qualified patient is observed closely, symptoms of gynecomastia are rare as are adverse issues related to mood and sexual complaints. It’s all about balance and vigilance! Another very important point regarding TRT and superphysiologic levels of estrogen is the potential for breast cancer! The good news is that there is no definitive data indicating that TRT associated elevations of estrogen lead to breast cancer in men. I can tell you that this is something that any expert physician Rxing Testosterone to men has to think about and better have on his radar screen!!

In addition to the mentioned side effects several others have been reported. In both males and females acne are frequently reported, as well as hypertrophy of sebaceous glands, increased tallow excretion, hair loss, and alopecia. There is some evidence that anabolic steroid abuse may affect the immune system, leading to a decreased effectiveness of the defense system. Steroid use decreases the glucose tolerance, while there is an increase in insulin resistance. These changes mimic Type II diabetes. These changes seem to be reversible after abstention from the drugs.

Anabolic steroid induced pancreatitis

anabolic steroid induced pancreatitis

In addition to the mentioned side effects several others have been reported. In both males and females acne are frequently reported, as well as hypertrophy of sebaceous glands, increased tallow excretion, hair loss, and alopecia. There is some evidence that anabolic steroid abuse may affect the immune system, leading to a decreased effectiveness of the defense system. Steroid use decreases the glucose tolerance, while there is an increase in insulin resistance. These changes mimic Type II diabetes. These changes seem to be reversible after abstention from the drugs.

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